Skip to main content

Nationwide replacement of High-Volume Chemistry analyzers: Immunoassays in Ontario

October 12 2022
We are pleased to share an update on our fall and winter plans to gradually replace the Roche Cobas and Abbott Architect analyzers used nationally for chemistry testing.

Dear health care providers,

We are pleased to share an update on our fall and winter plans to gradually replace the Roche Cobas and Abbott Architect analyzers used nationally for chemistry testing.  The testing performed on these analyzers includes clinical chemistry, immunoassays, and infectious disease (serology) assays at LifeLabs sites in Ontario. We are moving to the Abbott Alinity testing platform for these assays.

The first phase of this process took place in August 2022 with the move of Hepatitis and Rubella serology tests to the new Abbott Alinity i platform.

In the second phase, a number of immunoassays will transition to the Abbott Alinity i platform between October 24th, 2022 and November 30th, 2022Table 1 on page 2 provides a list of immunoassay tests that will be moving to the new testing platform, along with a description of notable changes.

Method validations were performed for all the immunoassays (noted in the Table below) at LifeLabs to ensure the assays meet our clinical requirements. The test results on the new analyzers compare well with our current platform.  A temporary notification will be included with all test results indicating a change in testing platform and highlighting any other significant changes (as applicable and described in Table 1 on page 2). This notification will be provided for 3 months from the date of implementation. Please note, minor updates to interpretive comments for some of the tests will also be implemented to align with current clinical guidelines and improve interpretation of laboratory results.

We will update you on additional changes impacting the LifeLabs chemistry testing as we get closer to the next phase of implementation in early 2023. For any clinical or technical questions regarding this change please contact the following LifeLabs biochemists:

Dr. Uvaraj Uddayasankar, PhD FCACB

Clinical Biochemist                      

T   416-675-4530 Ext. 42211

E uvaraj.uddayasankar@LifeLabs.com

Dr. Kika Veljkovic, PhD FCACB

Discipline Head, High Volume Chemistry

T   416-675-4530 Ext. 42832

Kika.Veljkovic@LifeLabs.com

 

Thank you,

Dr. Catherine Ross, MD, MSc, FRCPC

Medical Director, ON

T   647-943-2413 Ext: 42980

 

Table 1. Tests that are being transferred to the Abbott Alinity i platform in October 2022:

Test

Description of test change

BNP

Interpretive comments have been updated to reflect current guidelines on chronic heart failure.

Cortisol (Random, AM, PM)

Reference intervals have been changed to reflect current practice guidelines.

Estradiol

The test code for Estradiol (IVF) is no longer relevant and has been discontinued. There are no changes to the current testing protocols or interpretation.

Ferritin

Reference intervals have been updated to reflect recent practice guidelines.

The low limit of the reference intervals has been changed to reflect the diagnostic cut-off for iron deficiency and results will be flagged when they are below this limit. In addition, an interpretive aid is provided with all results indicating cut-offs for borderline iron deficiency in addition to diagnostic cut-off (derived from the WHO recommendations for iron deficiency).

FSH

No change

Homocysteine

Reference intervals are unchanged, with homocysteine results expected to be an average of 2 µmol/L lower than previous values.

In addition, a comment has been added for patients ≤ 18 years of age to aid in assay interpretation in the absence of an established reference interval for this age group.

LH

No change

NT-proBNP

No change

Progesterone

Reference intervals are unchanged except for the post-menopausal stage reference interval, which was updated based on studies by Abbott Diagnostics.

Prolactin

No change

Monomeric Prolactin (Macroprolactin)

No change

T3 free

No change

T3 total

No change

T4 free

No change

TSH

No change

Vitamin B12

Reference interval is unchanged, but a comment including common diagnostic cut-offs has been added to enhance interpretation of Vitamin B12 deficiency.

25OH Vit D

No change

Total PSA

No change

Free PSA (PSA Ratio)

No change

 

 

 

15

LifeLabs partners with Natera, Inc., to offer Signatera for genetic cancer testing

LifeLabs has partnered with Natera, Inc. to offer SignateraTM, a molecular residual disease test tha...
5

Updates and improvements related to A. Clinical Urine Drug Screen and B. Blood Glucose-6-Phosphate D...

LifeLabs BC has implemented a new analytical platform for clinical immunoassay-based urine drug scre...
24

Update on Chemistry Analyzers taking place at Burnaby lab between November 26 and 28

During this work, our patient service centres will remain open, however, please note there will be d...
25

BC Patient Service Centres Closed for the Remainder of October 25, 2022

Patient Service Centres in BC were closed at 2:30 PM today (October 25, 2022), due to an unplanned p...
25

Update on Replacement of Chemistry Analyzers in British Columbia

In November, we will be moving to the Abbott Alinity testing platform at our Burnaby Reference Lab (...
2

ASCORBIC ACID (ON) & VITAMIN C – PRIVATE PAY (BC)

**Update on Test Availability & Delay in Turnaround Time**
D...
18

LifeLabs reintroduces its Lactose Tolerance Hydrogen Breath Test
19

LifeLabs reintroduces Helicobacter pylori (H. pylori) Urea Breath Test

We’re pleased to share that LifeLabs has reintroduced its H. pylori Urea Breath test to its roster...
12

Review of Estimated Glomerular Filtration Rate (eGFR) Calculation

Client Notice: Recent evidence has emerged that suggests a reassessment of the formula for calculati...
6

FREE VALPROIC ACID (FREE VALPROATE)

Due to issues with our referral laboratory, Free Valproic Acid will temporarily be unavailable. We a...

HCPs
Newsletters

Read More
The stethoscope on the doctor's Desk

Scientific Publications

Read More
Scientist looking through a microscope in a laboratory


For rush results (NAAT within 12 hours and PCR within 24 hours)

  1. Order your FlyClear test and receive your FlyClear test requisition
  2. Book an appointment at a LifeLabs location below.
    • Bring your printed FlyClear requisition and Passport
    • Select your ordered Province’s Rush Test to start booking:
    British Columbia

    6084 Russ Baker Way
    Richmond near Airport

    COVID-19 PCR (24h) / Rush 12h NAAT

    Ontario

    6084 Russ Baker Way
    Richmond near Airport

    COVID-19 PCR (24h)
    Rush 12h NAAT
    Rapid Antigen (2h)

Pre-Departure testing now available from the comfort of your home with MyVisit (Currently Greater Toronto Area only)

  1. Order your FlyClear test and receive your FlyClear test requisition.
  2. Book your Home Visit appointment with the MyVisit portal or, if your flight is within the next five days, contact a MyVisit coordinator 1-416-993-9579 (Monday – Friday, 9am-5pm EST)

MyVisit Pre-departure testing offers:

  • COVID-19 PCR/NAAT swab testing
  • COVID-19 Antibody Blood (serology) testing

The MyVisit fee is $80 per person.

Pre-Departure testing

Book your appointment online here. If your flight is within the next five days and you have received your FlyClear requisition, please contact a MyVisit coordinator 1-416-993-9579 (Monday – Friday, 9am-5pm EST).

Your health & safety is important to us

Please note that face masks are mandatory at all times at all of our locations to ensure the health and safety of all customers and employees.

Please inform staff if you are unable to wear a mask due to a medical condition. 

Thank you for your cooperation!