Skip to main content

FIBROSIS-4 (FIB-4) INDEX AVAILABLE IN ONTARIO

November 22 2022
We’ve introduced the Fibrosis-4 (FIB-4) index in Ontario as a convenient testing option, with promising clinical utility in defining NAFLD patients with increased risk of clinically significant fibrosis.

We’re pleased to share that we’ve introduced the Fibrosis-4 (FIB-4) index in Ontario as a convenient testing option, with promising clinical utility in defining NAFLD patients with increased risk of clinically significant fibrosis and reducing unnecessary biopsies. It’s a simple, non-invasive, and readily available marker for the screening of liver fibrosis3-4. The FIB-4 score is calculated from AST, ALT, platelet count and age7.  This test can be highly beneficial for patients with the following conditions to be at high risk for NAFLD and advanced fibrosis5: obesity, metabolic syndrome, prediabetes, Type 2 Diabetes, hepatic steatosis on any imaging study, and persistently elevated ALT or AST levels (over 6 months).

 HOW TO ORDER

To order FIB-4, all 4 component tests must be ordered. If any are missed, the FIB-4 cannot be performed:

  • Write “FIB-4”, “FIB-4 index”, “Fib-4 Score”, “Fibrosis index”, or “Fibrosis score” in the “other tests” section of the standard OHIP requisition
  • Write “Aspartate aminotransferase (AST/ SGOT)” in the other tests section
  • Select Alanine aminotransferase (ALT/SGPT) on the OHIP requisition
  • Select Compete Blood Count (CBC) on the OHIP requisition.

Your patients can then make an appointment at a LifeLabs Patient Service Centre (PSC), or walk in, for their blood draw. Patients must present the OHIP requisition requesting the FIB-4, CBC, ALT, and AST signed by a physician or healthcare provider. (Specimen collection requirements are similar to ALT, AST and CBC).

Please note: 

  • The cost for this test is 10$ + 13$ for AST (unless patient meets criteria for insured AST). The FIB-4 index is not insured under OHIP. AST is only insured under OHIP when ordered by or on the advice of a physician with expertise in hepatic disorders.

REFERENCE RANGE AND RESULTS REPORTING

Turnaround time for results is within 1 day of specimen drop of. The following interpretive comment will be provided with FIB-4 index:

  • < 1.30: Low risk for advanced liver fibrosis
  • 30 – 2.67: Indeterminate risk for advanced liver fibrosis. May warrant further testing.
  • >2.67: High risk for advanced liver fibrosis. Warrants further testing.

Clinicians should consider further follow-up with transient elastography or ELF blood test in persons with increased risk of advanced fibrosis and indeterminate or high FIB-4 score. For more information, please contact our Ontario Customer Care Centre at: 1-877-849-3637.

Thank you,

Dr. Mohamed Abouelhassan PhD FCACB

Clinical Biochemist, Medical-Scientific Department – Ontario, Medical Laboratory Director

E   Mohamed.Abouelhassan@lifelabs.com

25

CD4/ CD8 TESTING

**Update in Turnaround Times** Due to a supply chain issue, there will be a temporary delay in tu...
23

LifeLabs’ online health portal MyCareCompass introducing a Health Assessment tool

We’re pleased to share with you the launch of a free Health Assessment tool in LifeLabs’ MyCareC...
22

FIBROSIS-4 (FIB-4) INDEX AVAILABLE IN ONTARIO

We’ve introduced the Fibrosis-4 (FIB-4) index in Ontario as a convenient testing option, with prom...
31

IMMUNOASSAY TESTING

**Update in Turnaround Times**
Due to the process involved ...
12

LifeLabs to offer electronic reports of LifeLabs Genetics Panorama™ Non-Invasive Prenatal Test (NI...

We’re pleased to share that we are enabling electronic reporting of LifeLabs Genetics’ Panorama...
12

Nationwide replacement of High-Volume Chemistry analyzers: Immunoassays in Ontario

We are pleased to share an update on our fall and winter plans to gradually replace the Roche Cobas ...
3

Updates and improvements related to Serum Beta-Carotene Testing

We are implementing a new test for beta-carotene performed using high performance liquid chromatogra...
26

Serum Androstenedione, Serum 17-hydroxyprogesterone, 24 hour urine Metanephrines, 24 hour urine cate...

**Update on Test Availability –Delay in Turnaround Time** Due to a supply chain shortage, there...
9

Consolidation of CBC/ESR and HbA1c Testing in South East, Champlain, North East, and North West comm...

Effective August 15TH 2022, Clients that perform phlebotomy in their own office and send samples to ...
1

Reintroducing Combined COVID and Respiratory Virus Testing Using Molecular PCR Technology

LifeLabs will be reoffering molecular PCR testing for the combined detection of COVID-19, Flu A, Flu...

HCPs
Newsletters

Read More
The stethoscope on the doctor's Desk

Scientific Publications

Read More
Scientist looking through a microscope in a laboratory


For rush results (NAAT within 12 hours and PCR within 24 hours)

  1. Order your FlyClear test and receive your FlyClear test requisition
  2. Book an appointment at a LifeLabs location below.
    • Bring your printed FlyClear requisition and Passport
    • Select your ordered Province’s Rush Test to start booking:
    British Columbia

    6084 Russ Baker Way
    Richmond near Airport

    COVID-19 PCR (24h) / Rush 12h NAAT

    Ontario

    6084 Russ Baker Way
    Richmond near Airport

    COVID-19 PCR (24h)
    Rush 12h NAAT
    Rapid Antigen (2h)

Pre-Departure testing now available from the comfort of your home with MyVisit (Currently Greater Toronto Area only)

  1. Order your FlyClear test and receive your FlyClear test requisition.
  2. Book your Home Visit appointment with the MyVisit portal or, if your flight is within the next five days, contact a MyVisit coordinator 1-416-993-9579 (Monday – Friday, 9am-5pm EST)

MyVisit Pre-departure testing offers:

  • COVID-19 PCR/NAAT swab testing
  • COVID-19 Antibody Blood (serology) testing

The MyVisit fee is $80 per person.

Pre-Departure testing

Book your appointment online here. If your flight is within the next five days and you have received your FlyClear requisition, please contact a MyVisit coordinator 1-416-993-9579 (Monday – Friday, 9am-5pm EST).

Your health & safety is important to us

Please note that face masks are mandatory at all times at all of our locations to ensure the health and safety of all customers and employees.

Please inform staff if you are unable to wear a mask due to a medical condition. 

Thank you for your cooperation!